ZCCHC7 Antibody - Western Blot Validated
BiCell Scientific
SKU:51377-WB-50UL
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Scientific Overview
This antibody is suited for researchers who want to investigate ZCCHC7 and relate it to cell-state biology. ZCCHC7 is a regulator within kinase-driven cascades that influence transcriptional and metabolic responses. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
Tracking ZCCHC7 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Research Relevance
Perturbations such as inhibitors or ligand stimulation can drive rapid shifts in localization or complex formation. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Because cellular networks are interconnected, changes in this target may coincide with shifts in related pathways, trafficking behavior, or structural remodeling. In oncology research models, expression shifts can accompany changes in adhesion, signaling, or differentiation state.
When building a narrative around the target, it helps to track:
- time-resolved changes following stimulation or inhibition
- interaction patterns within multi-protein complexes
- condition-to-condition comparisons with matched controls
Application-Specific Context
This denaturing-format version is geared toward targets presented after reduction and denaturation, where epitope exposure can shift from native conformations. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.
When interpreting ZCCHC7, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
Use the denaturing-format variant when your project demands ZCCHC7 readouts that respect preparation constraints.
- Targets:
- ZCCHC7
- Research Area:
- Cancer • Cell Signaling • DNA Damage / Repair
- Application:
- WB
- Reactivity:
- Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the C-terminal region of mouse ZCCHC7 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q8N3Z6
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 56.3% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C