ZCL278

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Selleck Chemicals

S7293-10MG

€154,00 EUR
€154,00 EUR
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ZCL278 is an inhibitor of Rho GTPases and Cdc42 used in studies of target-focused biology. It is especially relevant in cancer, cell cycle, and cell signaling models, where defined compound exposure can be linked to annotated target biology and downstream cellular responses.

By inhibiting Rho GTPases and Cdc42, ZCL278 can be used to examine annotated target biology and downstream cellular responses. That positioning is consistent with concentration-response inhibition and target-dependence studies and with follow-up studies that compare concentration-dependent responses across orthogonal assay formats. In cancer, cell cycle, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Rho GTPases and Cdc42
  • Concentration-response inhibition and target-dependence studies
  • Phenotypic profiling in cancer, cell cycle, and cell signaling models
  • Combination studies with orthogonal perturbagens

Overall, ZCL278 is appropriate when a defined chemical perturbant is needed to connect Rho GTPases and Cdc42 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell cycle, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Rho GTPases • Cdc42
Target Class:
Other
Research Area:
Cancer • Cell Cycle • Cell Signaling
CAS No.:
587841-73-4
Molecular Weight:
584.89
Formula:
C₂₁H₁₉BrClN₅O₄S₂
SMILES:
CC1=CC(=NC(=N1)NS(=O)(=O)C2=CC=C(C=C2)NC(=S)NC(=O)COC3=C(C=C(C=C3)Br)Cl)C
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.