ZINC00881524 (ROCK inhibitor)

1 1

Selleck Chemicals

S8448-5MG

€144,00 EUR
€144,00 EUR
Sale Sold out
Taxes included. Shipping calculated at checkout.
Size
View full details

ZINC00881524 (ROCK inhibitor) is an inhibitor of ROCK used in studies of kinase signaling. It is especially relevant in cancer, cardiovascular, and cell cycle models, where defined compound exposure can be linked to phosphorylation signaling, target engagement, and selectivity relationships.

By inhibiting ROCK, ZINC00881524 (ROCK inhibitor) can be used to examine phosphorylation signaling, target engagement, and selectivity relationships. This target class is commonly examined through biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping. In cancer, cardiovascular, and cell cycle models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving ROCK
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling
  • Phenotypic profiling in cancer, cardiovascular, and cell cycle models

Overall, ZINC00881524 (ROCK inhibitor) is appropriate when a defined chemical perturbant is needed to connect ROCK with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cardiovascular, and cell cycle models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
ROCK
Target Class:
Kinase
Research Area:
Cancer • Cardiovascular • Cell Cycle • Cell Signaling
CAS No.:
557782-81-7
Molecular Weight:
380.46
Formula:
C₂₁H₂₀N₂O₃S
SMILES:
COC1=C(C=C(C=C1)CC(=O)NC2=NC3=C(S2)CCC4=CC=CC=C43)OC
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.

The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.