Zoledronic acid monohydrate
Selleck Chemicals
SKU:S5244-25MG
Couldn't load pickup availability

Zoledronic acid monohydrate is an inhibitor of Rho GTPases used in studies of Apoptosis. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to caspase-associated cell-death signaling and survival decisions in apoptosis, cancer, and cell cycle models.
By inhibiting Rho GTPases, Zoledronic acid monohydrate can be used to examine caspase-associated cell-death signaling and survival decisions. This context is compatible with apoptosis, viability, and caspase-readout assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In apoptosis, cancer, and cell cycle models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving Rho GTPases
- Pathway perturbation studies connected to Apoptosis
- Concentration-response inhibition and target-dependence studies
- Phenotypic profiling in apoptosis, cancer, and cell cycle models
Overall, Zoledronic acid monohydrate is appropriate when a defined chemical perturbant is needed to connect Rho GTPases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and cell cycle models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- Rho GTPases
- Target Class:
- Other
- Pathways:
- Apoptosis
- Research Area:
- Apoptosis • Cancer • Cell Cycle • Cell Signaling
- CAS No.:
- 165800-06-6
- Molecular Weight:
- 290.1
- Formula:
- C₅H₁₀N₂O₇P₂·H₂O
- SMILES:
- C1=CN(C=N1)CC(O)(P(=O)(O)O)P(=O)(O)O.O
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.
The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.